What is ‘CRIB’? Know about never-seen blood group detected in 38-year-old Indian woman

The discovery appeared to be accepted to the RL Jalappa Hospital in Kolar for heart surgery in February last year.
According to a media report, a 38 -year -old woman from the Kolar region in Karnataka was defined as the first person in the world with an unknown and extremely rare blood group. Medical experts, if they need blood transfusion, no other individual does not have the same unique blood group should donate their own blood in advance, he said. The case was directed to the advanced immunohematology reference laboratory at the Rotary Bangalore Blood Center after it was proved to have failed to find a match.
What is Crib?
According to a report made by Hindu, experts in the laboratory observed an unusual reaction between blood and each tested sample and have never been documented before. More tests of family members could not give a match. The discovery appeared to be accepted to the RL Jalappa Hospital in Kolar for heart surgery in February last year.
During his treatment, he proved that the blood of the woman was incompatible with others. Even blood samples from family members were not a match. Later, doctors conveyed samples to the International Blood Group Reference Laboratory (IBRL) in the UK.
Using molecular techniques, after a comprehensive 10 -month analysis, he confirmed the presence of a new antigen in the laboratory blood. This new antigen is officially recognized as part of the Cromer (CR) blood group system.
Why was the blood group called Crib?
The antigen was called “CR” representing Cromer and “IB” showing Bengaluru, Bengaluru.
What are the side effects of this blood group?
The discovery was presented on 4 June 2025 at an international blood transfusion conference in Milan, Italy. Medical experts emphasized that if he needed another transfusion, he could not be due to blood donations from others. For programmed surgeries, it may need to increase their own hemoglobin levels and keep their blood in advance, which is known as autologous transfusion.
Rotary Bangalore TTK Blood Center launched a ‘Rare Blood Donor’ program to support individuals with rare blood types in cooperation with other organizations. They detected 21 rare donors from a pool of more than 2,000 people tested.



