Telltale Alzehimer’s warning sign your body might be giving you | Science | News

Scientists discovered new clues about the early symptoms of Alzheimer. Researchers in the spherical neurodegeneration proteomic consortium (GNPC) examined proteins in the body that could be used to monitor neurological diseases.

Works, published Nature MedicalPartly the billionaire was financed by Bill Gates, a charitable and founding partner of Microsoft. He told us that the discovery could be made closer to the day when the diagnosis of Alzheimer’s disease stopped being a death penalty than ever ”. Scientists knew that Apoe4, who had two copies of a certain gene -coding protein, increased Alzheimer’s ten -fold risk, but why they were not sure. However, researchers have now revealed their role in the reaction of inflammation and infection that could contribute to the disease. They also identified blood signatures that can safely confirm whether someone has copies of the high -risk Apoe4 gene.

His studies also support the theory that Alzheimer’s brain depends on the accumulation of certain proteins in the brain (amyloid and tau proteins).

“This paves the way for the discovery of drugs that can lead to new treatments.

“The most exciting part is that protein abnormal patterns that predict neurodegenerative diseases show new perspectives on biology about how these conditions develop.”

Simon Lovestone, Head of Global Discovery and Translation Studies in Johnson & Johnson, said that his studies will rapidly accelerate research in the field of neurodegeneration.

“The scale and depth of the data set combine with harmonious clinical data, making neurodegenerative diseases an extraordinary source of the potential to examine, detect and treat,” he said.

The study is part of the Global Neurodegeneration Proteomic Consortium, an initiative established in 2023. Research institutions were brought together with the support of Johnson & Johnson and Gates Ventures.