Why scientists say slimming jabs could ease the pain of arthritis – even if you’re not overweight

Arthritis patients can relax from painful symptoms using weight loss jabs.

It has been shown that drugs prescribed for obesity and type 2 diabetes treatment such as Mounjaro and Wegovy significantly reduce the risk of a number of diseases, including heart attack and stroke for the last few years.

And it is understood that rheumatoid arthritis, which is now known as GLP-1 agonists, attacks the healthy joint tissue of the immune system and causes painful swelling, can alleviate painful symptoms.

Last week, a study published in the American Rheumatology College Journal of Semagluid or Tyrzipathide in low doses – active ingredients in drugs – found significant decreases in pain.

Professor Andrew Cope, a rheumatologist at King’s College London, said, “ There is a really good evidence that these drugs can reduce inflammatory cells in the body, ” he said. ‘This study showed reduced pain, especially in non -overweight patients, around 27 BMI. Most patients in the clinic are on this, so the effects on those who really struggle with weight may be even greater.

In rheumatoid arthritis, we know that these drugs can prevent the production of specific cells that trigger exacerbations such as existing drugs-but they also have extra anti-inflammatory properties. They are really a great medicine in many ways. ‘

Experts say that findings can change the way rheumatoid arthritis is treated.

Professor Cope added: ‘The use of these drugs will definitely expand and offer us the opportunity to better personalize care for rheumatoid arthritis. Although they do not replace existing drugs, they can prove an effective tool used. ‘

More than 1.3 million people have rheumatoid arthritis in the UK. The most common symptoms are joint pain, swelling and hardness – typically on hands and feet. Many patients also experience fatigue, sweating and weak appetite.

The probability of developing the situation of women is three times higher than men and usually works in families.

There is currently no treatment, but drugs are prescribed to control symptoms. Weight loss jabs are not among them-but some patients who prescribe obesity injections report dramatic developments.

American mother, 30 -year -old Cassandra Smith says that her life has been transformed by Tirzepathide. Three years ago, the teacher was diagnosed with rheumatoid arthritis and was usually left to bed by flames.

“ Pain will begin on my shoulders and slowly move down my body, sometimes would take three days to move again ‘he said.

Cassandra, which weighs more than 22 stones, was told by the rheumatologist to reduce symptoms of weight loss. However, after trying various diet programs without being successful, he was prescribed nine months ago.

“Within three weeks, the tests showed that my inflammation returned to normal, and two weeks after all the pain went,” he said. “ `I went not to take one in months of exacerbations. He changed my life. ‘

The biggest benefit is likely to be for patients with both rheumatoid arthritis and obesity. However, in accordance with the existing NHS rules, they are not suitable for jabs.

King’s College London Rheumatology Researcher Professor James Galloway, “ “ In the clinic, the proportion of patients with obesity is increasing, ” he said. ‘Approximately half are considered obese. Existing drugs are usually less effective in these patients due to partially higher dose and extra weight load.

‘Nevertheless, arthritis is currently not listed as a co-morbidity that allows access to these drugs in NHS.’

NHS Guidelines Status Patients must have at least four health status such as heart disease or type 2 diabetes to qualify for over 40 BMI and JABs.

Professor Galloway, “ This will change, but we need more ongoing research, ‘he said.

Arthritis and Arthritis Research Director Lucy Donaldson attracted attention. He said: ‘We are watching the research, but there is not enough evidence to know how they interact with the effects of weight loss injections or how they interact with existing treatments.

‘This work is interesting, but there are limitations that make it difficult to make sure that the GLP-1 agonists have direct contributions.

‘We recommend that anyone who uses or intends to use weight loss medications should do so with information and support of medical practitioners.

‘These drugs have side effects and risks and should be taken only under clinical control, as well as lifestyle changes such as a healthy diet and appropriate physical activity.’