Christina Applegate, 54, is ‘hospitalized’ amid MS battle… after revealing she is largely confined to her bed with the disease

Christina Applegate has been ‘hospitalised’ during her ongoing battle with multiple sclerosis (MS).

Sources told TMZ It was stated that the 54-year-old actress was hospitalized late last month, but the reason for this has not yet been disclosed.

Applegate’s representative told the Daily Mail: ‘I have no comment on whether he is in hospital or what his medical treatments are.

‘As evidenced in his memoirs and podcast, he had a long history of dealing with complex medical conditions and was refreshingly open about it.’

The married actor with children announced his diagnosis of chronic autoimmune disease in 2021.

And a few months ago in February, Applegate heartbrokenly shared that she was mostly confined to her bed due to her MS battle.

During an interview with People At the time, the star explained how the pain largely kept her in bed.

But he’ll do whatever he can to leave the bedroom to his teenage daughter, Sadie – like taking her to school.

‘I want to take it; This is my favorite thing to do. This is the only time we spend together alone,” the actress told the press.

‘I tell myself: ‘Get him there safely and go home so you can go back to bed.’ That’s what I’m doing.’

Applegate also stated: ‘My life is not wrapped up in a bow. People’s lives, I’m sorry for lack of a better term, suck sometimes. So I’m being as honest and raw as I can.’

Multiple sclerosis occurs when ‘the immune system attacks the protective sheath that covers nerve fibers known as myelin’. Mayo Clinic.

The disease ‘can cause lethargy, weakness, difficulty walking, vision changes and other symptoms.’

The Dead To Me actor also reflected on his MS battle with a quote from his 2026 memoir, You With The Sad Eyes. Guard In March.

Applegate’s representative told the Daily Mail: ‘I have no comment on whether he is in hospital or what his medical treatments are’; Spotted in Los Angeles in 2023

And a few months ago in February, Applegate heartbrokenly shared that she was mostly bedridden due to her battle with MS.

Applegate wrote candidly: ‘One of the worst side effects of the disease is exhaustion.

‘It’s like I’ve been sleep deprived for three days and this is how I feel after a good night’s sleep. So I spend all my time in bed and leaning on my heating pad.’

He continued: ‘After this diagnosis and the symptoms I’ve encountered, I no longer care what I say, how I come across, or how it makes someone feel.

‘I no longer have patience for bulls***, things that are meaningless or just “extra”.’

Applegate shared the news of her MS diagnosis on social media in August 2021.

‘Hello friends. A few months ago I was diagnosed with MS. It was a strange journey. “But I’ve had so much support from people, I know who has this condition, too,” he explained at the time.

‘It’s been a touching journey. “But as we all know, the road continues,” said the star, showing his positivity about his health condition.

During part of it MeSsy podcast Last year, the actor revealed that he was hospitalized multiple times during his MS battle.

The Dead To Me actor also touched on his MS battle in an excerpt from his 2026 memoir You With The Sad Eyes, published in The Guardian in March; Spotted in Los Angeles in 2023

“I’ve been in the hospital over 30 times over the three years since I was diagnosed,” he told fellow host Jamie-Lynn Sigler, who is also battling the disease.

‘This is unimaginable, okay? ‘They did every known test on me, put a lot of radiation into my body, from CT scans to everything else.’

And he recorded an episode of the podcast from his hospital bed in August 2025 while being treated for a kidney infection.

After a trip to Europe with his family, he went to the hospital because he was not feeling well.

“I want to be accepted,” Applegate explained. ‘I’m staying here because I want answers. ‘I want every test you can think of, or any tests you haven’t even thought of, and I want them done.’

The actor recalled that when he woke up, he felt severe pain on his right side, which caused him to “scream”.

After undergoing an emergency CT scan, it turned out he had a kidney infection.

As for writing the memoir, which was released on March 3, Applegate previously shared that she decided to write the book at a time when she was “forced to slow down.”

He continued: ‘Given this diagnosis and the symptoms I’m experiencing, I no longer care what I say, how I come across, or how it makes someone feel.’

“I’ve been in the hospital over 30 times over the three years since I was diagnosed,” he told co-host Jamie-Lynn Sigler, who also battles the disease; Seen with daughter Sadie in Los Angeles in 2023

‘I’ve had a career in television and film since I was 3 years old and I’ve loved it. The Emmy-nominated actress said that everything I thought was important changed with MS. People.

‘For a long time, I felt it was impossible to find meaning in everything I was experiencing, but for the first time in my life, I was able to stop and think.’

The star also admitted that “telling everything” was “scary” in her candid memoirs.

‘But no matter how dark it was, I wrote this because I truly believe books can make people feel less alone.’