Christina Applegate Hospitalized in LA Amid Her Battle With Multiple Sclerosis

Actor Christina Applegate was hospitalized in Los Angeles during her ongoing battle with multiple sclerosis (MS), according to TMZ. Applegate was accepted in late March, according to the publication. However, the exact reason for his hospital stay was not made public. It is also unclear whether his hospitalization was linked to his MS condition.

The update comes shortly after Applegate’s podcast co-host Jamie-Lynn Sigler shared on March 31 that their podcast, MeSsy, would be taking a brief hiatus while both hosts are busy with book tours. Sigler has been living with relapsing MS for more than two decades. Updated: Apr 13, 2026 21:02 IST Jennifer Lopez makes surprise appearance at Coachella during David Guetta performance Reacting to the reports, Christina Applegate’s rep told TMZ: “I have no comment on whether she was in the hospital or what her medical treatments were. She had a long history of complex medical conditions, as evidenced in her memoir and podcast, and was refreshingly open about it.” Updated: 12 Apr 2026 20:54 IST “An artist who inspires us all with her zeal”: Sonu Nigam gets emotional remembering that Asha Bhosle Applegate was diagnosed with multiple sclerosis in June 2021. Since then, she has spoken openly about the physical and emotional challenges the disease brings. Last month, he published his memoir, ‘You with Sad Eyes’, in which he shared details about how the disease affected his daily life. “When I wake up, I often can’t move my arm enough to grab a glass of water next to my bed or my phone from its charger,” she wrote in the book.

He also shared that the disease made him more prone to infections and that he had to go to the emergency room regularly.