Breakthrough blood pressure treatment found to work even when others fail
A new medicine It was found to be significantly lower blood pressure In humans dangerously high Despite taking a few drugs existing, a progress that is difficult to treat hypertension cases.
Approximately half of the global high blood pressure cases treatment -resistantSuch patients face a much greater risk. heart attack– paralysisKidney disease and early death.
Now, researchers have shown that Baxdrostat, a new pill, can make patients’ blood pressure bigger enough to reduce the risk of heart disease.
The phase III clinical study, which includes the participation of approximately 800 patients in 214 clinics around the world, found that BAXDROSTAT, which is 1 mg or 2 mg of BAXDROSTAT, fell about 9-10 mmhg more than the placebod.
Tyler Williams, Terre Haute, Terre Haute, Indiana (Getty Images) Terre Haute South High School at Terre Haute South High School in a remote region in a remote region in a remote region controlled blood pressure in a remote region.
The researchers noticed that approximately 4 of 10 patients have reached a healthy blood pressure level compared to less than 10 on placebo.
“In the BAXHTN phase III study, it is exciting to obtain a decrease in systolic blood pressure with BAXHTN Phase III, because this reduction level is significantly lower than the risk of heart attack, stroke, heart failure and kidney disease.” He said.
“In patients with uncontrolled or resistant hypertension, the addition of Baxdrostat 1mg or 2mg once a day to background antihypertensive treatment caused clinically significant significant decrease in systolic blood pressure that continued up to 32 weeks without unexpected safety findings.” He said.
Findings also reveal the role of key hormone in cases of blood pressure that are difficult to control in millions of patients.
“These findings are an important progress in treatment and understanding the cause of blood pressure that is difficult to control.” He said.
In our body, a hormone called aldosterone manages blood pressure by helping the kidneys to regulate salt and water balance.
In some people, too much aldosterone is produced that causes the body to be kept in salt and water and pushes blood pressure.
It has been difficult for decades to achieve a balance at the level of drug use of this hormone.
The new drug Baxdrostat works by preventing aldosterone production and directly taking this regulator of this high blood pressure.
“There is no control of about half of the people treated for hypertension, but this is a conservative estimation because this is much lower than that the target we are trying to reach is much lower than before.” He said.
“The results show that this drug can potentially help half a billion people globally and only in the UK, especially at the new target level for optimal blood pressure control.” He said.
