Overweight adolescents susceptible to cardiac events as adults? Preliminary study by KMCRI finds elevated risk markers

A pre-study taken by the Karnataka Medical College and Research Institute (KMCRI), operated by the State, revealed that the majority of adolescents-especially the extremely overweight students-biochemical profiles include biochemical profiles showing the increasing risk of cardiac event.

In February 2025, KMCRI’s multiple disciplined research unit (MDRU), Cardiovascular Diseases (CVDs), although it was generally accepted as discomfort of puberty areas, took over the study among adolescents after the latest trends.

The aim of the study is to evaluate the symptoms of early cardiovascular metabolic risk among adolescents going to school in Dharwad. The researchers team chose 30 asymptomatic, overweight students from VIII and IX class drawn from six schools in both urban and rural areas of the region. Children were scanned for early biochemical and clinical indicators associated with cardiovascular risk.

Worrying findings

Although the sample size was small, the findings for the team led by Mdru Nodal Officer Ram Kaulgud and common assistant Manjunath Nekar were very concern. During a one -month study, in addition to taking blood samples, team members gathered details about the lifestyle, routine activities, screentime, food habits and other related aspects.

One of the 30 students scanned was diagnosed with diabetic and four hypertension. Scanning also revealed lipid profile abnormalities among students. The study found high total cholesterol for five students and 11 students have high levels of triglyceride with a high value of 499 mg/dL. This separate, LDL cholesterol rose to five students.

Cardiac Risk

The study showed that 26 out of 30 students increased the ‘homocysteine’ levels, which increased the risk of cardiovascular disease. High lipoprotein (A) was found in four students. Furthermore, ‘high sensitivity C-Reactive Protein’ (HSCRP), an inflammation and cardiac risk marking significantly increased significantly in 18 students, which has biochemical profiles indicating that more than 80% of the participants increased the risk of cardiac event.

The preliminary study concluded that even in the absence of open symptoms, there was an worrying prevalence of subclinical cardiac risk factors among adolescents and emphasized the need for emergency public health interventions, lifestyle changes and routine cardiac risk scanning in school health programs.

For the other Mrus for rope

Now, after the preliminary work, KMCRI wants to go to a larger example in coordination with other MRUS in other medical colleges and other MRUS in hospitals.

KMCRI DR SF Kammar Director, “We received appreciation by the Indian Medical Research Council (ICMR) for this preliminary study (ICMR) and the leading medical research organization advised us to continue more. Hindu.