Liver disease crisis: 130 crore people already affected; what we eat and how we live may worsen the risk by 2050
The findings are based on data from the Global Burden of Disease Study, one of the most comprehensive global health datasets tracking disease trends and risk factors.
MASLD cases expected to reach 1.8 billion by 2050
Researchers have warned that the prevalence of MASLD could rise to around 1.8 billion cases by 2050. The projected increase is largely attributed to rapid population growth, increasing rates of obesity, and increasing levels of high blood sugar and metabolic disorders.
Lifestyle changes associated with urbanization, sedentary habits, and poor eating habits are the main factors driving the increase in MASLD cases worldwide.
Higher prevalence of MASLD in North Africa and the Middle East
The study found that regions such as North Africa and the Middle East witnessed disproportionately higher rates of MASLD compared to other parts of the world. Experts believe this trend is closely linked to changing lifestyles, dietary habits and limited access to preventive healthcare in certain areas.
Stable disease burden despite increasing MASLD cases
Interestingly, while the number of MASLD cases has increased significantly, the overall health burden, measured by years lost to disease or premature death, has remained relatively constant.
Researchers suggest that advances in medical care, early diagnosis, and improved disease management are helping patients live longer, healthier lives, especially in the early stages of the disease.
Increased risk of liver cirrhosis and liver cancer
Despite these advances, experts warn that the increasing number of cases of MASLD poses a long-term risk. A larger patient pool increases the likelihood of serious complications such as liver cirrhosis and liver cancer in the future.
Early stage detection does not eliminate risks, especially if lifestyle factors are not addressed.
MASLD increasingly affects young adults in developing countries
Another worrying trend highlighted in the research is the increasing prevalence of MASLD among young adults, especially in low- and middle-income countries. Rapid urbanization, processed food consumption, and decreased physical activity are accelerating the spread of metabolic disorders in these regions.
MASLD is a global health priority that requires urgent action
The researchers emphasized the urgent need to recognize MASLD as a global public health priority. They called for targeted health policies, increased awareness campaigns and preventive interventions to reduce risk factors such as obesity and diabetes.
Strengthening health systems and promoting healthier lifestyles will be crucial in reducing the long-term impact of MASLD.
Key statistics highlight worrying MASLD growth
The study noted that MASLD affects approximately 16.1 percent of the global population in 2023. The age-standardized prevalence rate increased significantly compared to 1990, underlining the rapid spread of this metabolic liver disease.
As global health systems grapple with the increasing burden, experts warn that without timely intervention, MASLD could become one of the leading causes of chronic liver disease worldwide.
Inputs from PTI
