‘Tremendous uncertainty’ for cancer research as US officials target mRNA vaccines | Trump administration

As US regulators restrict Covid MRNA vaccines and independent vaccine consultants re -examine the shooting, scientists fear that an unexpected goal may be the next: cancer research.

Messenger RNA or MRNA, vaccines, pancreatic cancer, brain tumors and others, such as the treatment and prevention of cancers, which are often difficult to address, promised hope.

However, groundbreaking research, federal and state officials may target MRNA attempts, including the termination of federal funds for bird flu MRNA vaccines, to restrict who can receive existing MRNA vaccines, and to propose laws against vaccines in some places.

The Trump administration has applied unprecedented interruptions in cancer research as well as widespread layoffs in other research interruptions and National Health Institutes (NIH).

According to the crowded project, at least 16 grants containing the word “mRNA ına were terminated or frozen Grant Watchand scientists were told to remove the words of MRNA vaccines from research practices, KFF Health News reported In March.

Researchers are afraid that therapeutic cancer vaccines will be “sweeping in this tidal wave” against the MRNA vaccines, and Stony Brook University Surgical Oncology Chief Aaron Sasson said in April.

In the case of MRNA breakthroughs, Eli The most critical of the next few years ”is Elias Sayour, a professor of Pediatric oncology at the University of Florida.

“Our progress so far – which is stopped – if it is stopped or if Stysyigned, it can definitely affect the orbit and the arc.”

Authorized, the uncertainty around MRNA and in general research, researchers and institutions can deterd the start of new projects, he said.

Orum If we continue to take over these gains in the next 10, 20 years, I see a scenario where we completely transform how we look at a great human disease field, ”he said.

Research on MRNA Cancer Vaccines Continues More than ten yearswith more 120 Clinical Study Treatment and prevention of cancers. MRNA shots promised hope to prevent return head and neck cancer; lymphoma; breast cancerIt constitutes 11.6% of all cancer deaths in the United States; Colorectal cancer; lung cancer; And kidney cancerAmong others.

Pancreatic cancer has a 10% survival rate and is the second leading cause of cancer deaths in the USA, but small workApproximately half of the patients receiving MRNA vaccine did not see cancer turns, and three years later they had strong immune reactions.

Early MRNA Vaccine Trials, melanoma can be cut half. And a small work written by Sayour glioblastoma He showed that he started to affect tumors within 48 hours.

Like any vaccine, MRNA cancer vaccines train the body to recognize and destroy harmful cells.

Unlike foreign pathogens such as infectious diseases, cancer is caused by the growth of the patient’s own cells.

Some cancer vaccines are highly personalized to educate these dangerous cells using a patient’s own cancer cells to treat tumors or repeats these dangerous cells.

“There is an enormous, tremendous promise of the ability to create special vaccines for patients, but this is not possible five or 10 years ago, Sass Sasson said. “This is a change in the paradigm we really treat cancers.”

Researchers also investigate the vaccines that will target cancer cells more broadly by identifying “fingerprints ın of some cancers.

In addition, vaccines can be created for other conditions such as type 1 diabetes and multiple sclerosis.

“It has the potential to get rid of too much chronic morbidity to treat degenerative diseases, overcome cancer evolution and to heal patients,” he said. “MRNA may be the health service that the press -type printing press is for human knowledge.”

However, Federal and State decision -makers have targeted MRNA vaccines in recent months.

US Food and Drug Administration (FDA) Biological Evaluation and Research Center Director Vinay Prasad, reported exceed scientists In the agency, to limit some Covid vaccines to children over 12 years of age, including a new MRNA from Moderna. Prasad imposed similar restrictions on Covid, which does not use MRNA from Novavax.

On Thursday, FDA approved the original Covid MRNA vaccine for children between the ages of six months and 11 from Modernna – but they narrowed their use to children with at least one underlying situation. (Vaccine for people over the age of 12 was approved in 2022.)

Prasad argued that Covid risks have fallen in two recent notes by the FDA, and that the “known and unknown” side effects could overweight the benefits of vaccination.

Covid continues to be a leading cause of death in the United States. 178 Death US Disease Control and Prevention Centers (CDC) (CDC) offers complete data in the week ending on June 7 last week.

At the meeting of the CDC’s immune applications Advisory Committee (ACIP) in June, the new vaccine consultants appointed by Robert F Kennedy JR, Secretary of Health and Human Services (HHS) after firing the previous 17 advisors, increased the safety of Covid MRNA vaccines, which showed the future of these shoots.

Vicky Pebsworth, a registered nurse who has been volunteer for years with the National Vaccination Information Center, said that he was “very concerned about the side effects of Covid MRNA shots and asked for more data about security, including“ reproductive toxicity ”.

Shortly before the appointment of Acıp, the founder of Pebsworth and the National Vaccination Information Center argued that FDA should not propose MRNA COVİD-19 shots for everyone.

Retsef Levi, a professor of operations management at the MIT Sloan Management School at the June Acıp meeting, said that the side effects of MRNA believes that even when you normalize the number of doses, he believes that other vaccines were reported in excess. ”

Previous Levi controversial: “Evidence is indisputable that MRNA vaccines cause serious damages, including death among young people.

Another new ACIP consultant Robert Malone, repeatedly controversial against MRNA vaccines.

In 2021, Kennedy, then anti -vaccine organization Head of Child Health Defense, petition FDA is to cancel the approval of all Covid vaccines and prohibit future approvals. He has named Covid expenses the “the most deadly vaccine ever done.”

In May, Kennedy changed Covid vaccine suggestions from “compulsory” to “May için for children and completely eliminated the proposal for pregnant women.

Again in May, the United States canceled 766 million dollars of contracts for research on MRNA vaccines against H5N1 bird flu. HHS Communication Director Andrew Nixon said that the investment in the MRNA vaccine is not “scientific or ethical right”. expressions He added that “MRNA technology has been sufficiently tested ada to the media.

Millions of MRNA vaccines have been given worldwide and have been shown to be safe and effective in multiple studies.

Prohibitions or restrictions were introduced in MRNA vaccines Seven states. Such an invoice Idaho For 10 years, he tried to pause “gene therapy vaccines – – a category in which they incorrectly place Covid vaccines and affect other therapeutics.

Similarly, in the state of Washington, the commission members in Franklin County resolution Calling to stop the provision and promotion of the local health facility’s gene therapy vaccines; They also incorrect Covid MRNA shots in this category.

Sasson said, “There is currently this roasted soil mentality, but I hope that after the dust is settled, we can allow or allow vaccination to progress for cancer purposes,” Sasson said.

Cancer the second leading The cause of death in the USA and Two out of five Some kind of cancer will be diagnosed during their lives.

There are currently only two FDA approved vaccines to prevent Cancer-Hepatitis B and Human Papillomavirus (HPV)-and both are targeted by vaccine anti-activists.

In January, Trump hosted Stargate AI’s launch at the White House. Larry Ellison, the president of the technology company Oracle, which is included in the project, can ultimately define cancers and develop MRNA vaccines.

The project will be financed by the private dollar, not a federal, but will benefit from research on cancer and MRNA as well as other fields of cancer.

However, Trump management has reduced other critical financing for cancer research, prevention and treatment.

In the first three months of the period, the administration canceled more than $ 180 million through the National Institute of Cancer (NCI) and proposed to cut 2.7 billion dollars from the cancer center in the next NIH budget.

The management has reduced financing for some family planning providers, which often scans for HPV and other cancer markers.

MPs also made tremendous deductions for medicaid and insurance through the appropriate maintenance law (ACA), which may mean waiting for longer or giving up for cancer treatment of uninsured and uninsured persons.

“There is a potential for great damage, big public health problems will be put aside during the approach to cancel the wide research,” Sasson said. “There are significant damages that will occur with these comprehensive changes.”

Sasson said, “There is an enormous uncertainty about how the future will look,” Sasson said for scientists who are still financing or entering the field.

However, optimistic that MRNA vaccines may progress for cancer and other diseases.

Scientists are often described as financing deductions, but this is not completely true, Say Sayour said, “Many people in my field are just trying to survive because they are just trying to survive.

Sayour reiterated concerns about both indirect and direct forces, shaping progress in MRNA vaccines.

“But I also want to be optimistic about our best days in front of us,” he said.